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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK1
All Species:
14.85
Human Site:
S947
Identified Species:
27.22
UniProt:
Q96PY6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PY6
NP_036356.1
1258
142828
S947
T
I
Q
E
N
E
V
S
E
D
G
V
S
S
T
Chimpanzee
Pan troglodytes
XP_001153129
1258
142786
S947
T
I
Q
E
N
E
V
S
E
D
G
V
S
S
T
Rhesus Macaque
Macaca mulatta
XP_001082793
1258
142958
S947
T
I
Q
E
N
E
V
S
E
D
G
V
S
S
T
Dog
Lupus familis
XP_543184
1286
146207
S975
T
V
Q
Q
N
E
V
S
E
D
E
I
P
M
N
Cat
Felis silvestris
Mouse
Mus musculus
P51954
1203
136672
I899
S
E
V
C
E
D
R
I
P
G
N
V
D
Q
S
Rat
Rattus norvegicus
NP_001099552
648
74414
E360
E
E
R
K
K
M
S
E
E
A
A
K
K
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513277
864
98961
E576
H
E
N
A
A
G
E
E
M
E
N
D
T
L
N
Chicken
Gallus gallus
XP_420401
1281
145243
A967
D
E
N
L
V
S
I
A
H
F
S
Y
L
L
H
Frog
Xenopus laevis
Q7ZZC8
944
104521
W656
A
D
N
H
I
F
A
W
G
N
G
G
N
G
R
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
F409
S
V
S
C
G
D
L
F
T
T
C
L
T
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782796
1091
120115
A803
P
P
S
P
S
R
P
A
W
K
A
A
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
S318
F
R
G
N
L
E
D
S
V
S
S
I
K
K
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
S570
S
L
N
S
Q
Q
N
S
N
V
L
P
I
H
G
Conservation
Percent
Protein Identity:
100
99.6
97.5
85
N.A.
79.2
45.9
N.A.
30.2
66.2
22.4
22.7
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
99.7
98.4
90.8
N.A.
85.6
48.5
N.A.
44.3
78
39.2
34.4
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
100
100
100
53.3
N.A.
6.6
6.6
N.A.
0
0
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
73.3
N.A.
26.6
20
N.A.
13.3
13.3
20
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
35.1
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
0
8
16
0
8
16
8
0
0
0
% A
% Cys:
0
0
0
16
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
8
0
0
0
16
8
0
0
31
0
8
8
8
0
% D
% Glu:
8
31
0
24
8
39
8
16
39
8
8
0
0
0
0
% E
% Phe:
8
0
0
0
0
8
0
8
0
8
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
8
0
0
8
8
31
8
0
8
8
% G
% His:
8
0
0
8
0
0
0
0
8
0
0
0
0
8
8
% H
% Ile:
0
24
0
0
8
0
8
8
0
0
0
16
8
0
0
% I
% Lys:
0
0
0
8
8
0
0
0
0
8
0
8
16
8
0
% K
% Leu:
0
8
0
8
8
0
8
0
0
0
8
8
8
16
0
% L
% Met:
0
0
0
0
0
8
0
0
8
0
0
0
0
8
0
% M
% Asn:
0
0
31
8
31
0
8
0
8
8
16
0
8
0
16
% N
% Pro:
8
8
0
8
0
0
8
0
8
0
0
8
8
0
0
% P
% Gln:
0
0
31
8
8
8
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
8
8
0
0
8
8
0
0
0
0
0
0
8
24
% R
% Ser:
24
0
16
8
8
8
8
47
0
8
16
0
31
31
16
% S
% Thr:
31
0
0
0
0
0
0
0
8
8
0
0
16
0
31
% T
% Val:
0
16
8
0
8
0
31
0
8
8
0
31
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _